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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K7
All Species:
16.67
Human Site:
T448
Identified Species:
33.33
UniProt:
O43318
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43318
NP_003179.1
606
67196
T448
Q
D
L
T
V
T
G
T
E
P
G
Q
V
S
S
Chimpanzee
Pan troglodytes
XP_001160138
472
51727
N326
F
M
D
I
A
S
T
N
T
S
N
K
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001099744
609
67549
T448
Q
D
L
T
V
T
G
T
E
P
G
Q
E
N
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q62073
579
64209
T421
Q
D
L
T
V
T
G
T
E
P
G
Q
V
S
S
Rat
Rattus norvegicus
P0C8E4
606
67182
T448
Q
D
L
T
V
T
G
T
E
P
G
Q
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507638
595
66386
T437
Q
D
L
S
V
A
G
T
E
S
N
Q
V
S
S
Chicken
Gallus gallus
XP_001233491
604
67342
Q438
Q
Q
R
R
R
S
I
Q
D
L
T
V
A
G
T
Frog
Xenopus laevis
Q7T2V3
1005
111856
L589
G
E
E
R
L
K
T
L
G
E
G
N
K
Q
W
Zebra Danio
Brachydanio rerio
NP_001018586
544
61104
A397
R
S
V
Q
D
L
P
A
I
G
T
D
A
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Q6
678
75656
D431
D
V
E
A
N
G
F
D
L
S
P
S
E
S
S
Honey Bee
Apis mellifera
XP_397248
510
58111
E364
E
C
D
P
N
A
W
E
L
P
N
S
D
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795629
463
51420
Q317
H
P
T
P
S
H
P
Q
P
P
I
P
G
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.4
99.5
N.A.
N.A.
95
99
N.A.
91.4
91.7
21.9
70.6
N.A.
34.5
41.4
N.A.
39.9
Protein Similarity:
100
75.7
99.5
N.A.
N.A.
95
99.3
N.A.
93.7
93.7
35.7
77.8
N.A.
52.2
58.7
N.A.
51.4
P-Site Identity:
100
0
80
N.A.
N.A.
100
100
N.A.
73.3
6.6
6.6
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
20
86.6
N.A.
N.A.
100
100
N.A.
80
26.6
20
20
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
17
0
9
0
0
0
0
17
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
42
17
0
9
0
0
9
9
0
0
9
9
9
0
% D
% Glu:
9
9
17
0
0
0
0
9
42
9
0
0
17
0
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
42
0
9
9
42
0
9
9
0
% G
% His:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
9
0
9
0
0
0
9
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
9
9
0
9
% K
% Leu:
0
0
42
0
9
9
0
9
17
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
9
0
0
25
9
0
9
0
% N
% Pro:
0
9
0
17
0
0
17
0
9
50
9
9
0
17
0
% P
% Gln:
50
9
0
9
0
0
0
17
0
0
0
42
0
9
9
% Q
% Arg:
9
0
9
17
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
9
17
0
0
0
25
0
17
9
50
50
% S
% Thr:
0
0
9
34
0
34
17
42
9
0
17
0
0
0
17
% T
% Val:
0
9
9
0
42
0
0
0
0
0
0
9
34
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _